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Regulation of transcription | Biomolecules | MCAT | Khan Academy
 
06:47
Created by Tracy Kim Kovach. Watch the next lesson: https://www.khanacademy.org/test-prep/mcat/biomolecules/gene-control/v/post-translational-regulation?utm_source=YT&utm_medium=Desc&utm_campaign=mcat Missed the previous lesson? https://www.khanacademy.org/test-prep/mcat/biomolecules/gene-control/v/dna-and-chromatin-regulation?utm_source=YT&utm_medium=Desc&utm_campaign=mcat MCAT on Khan Academy: Go ahead and practice some passage-based questions! About Khan Academy: Khan Academy offers practice exercises, instructional videos, and a personalized learning dashboard that empower learners to study at their own pace in and outside of the classroom. We tackle math, science, computer programming, history, art history, economics, and more. Our math missions guide learners from kindergarten to calculus using state-of-the-art, adaptive technology that identifies strengths and learning gaps. We've also partnered with institutions like NASA, The Museum of Modern Art, The California Academy of Sciences, and MIT to offer specialized content. For free. For everyone. Forever. #YouCanLearnAnything Subscribe to Khan Academy’s MCAT channel: https://www.youtube.com/channel/UCDkK5wqSuwDlJ3_nl3rgdiQ?sub_confirmation=1 Subscribe to Khan Academy: https://www.youtube.com/subscription_center?add_user=khanacademy
Views: 270574 khanacademymedicine
Regulation of Gene Expression: Operons, Epigenetics, and Transcription Factors
 
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We learned about gene expression in biochemistry, which is comprised of transcription and translation, and referred to as the "central dogma" of molecular biology. But how is this process regulated? How does a cell know which genes to express and when? Well it's pretty complicated, but let's just get our feet wet by looking at operons, epigenetics, and transcription factors! Subscribe: http://bit.ly/ProfDaveSubscribe [email protected] http://patreon.com/ProfessorDaveExplains http://professordaveexplains.com http://facebook.com/ProfessorDaveExpl... http://twitter.com/DaveExplains Biology Tutorials: http://bit.ly/ProfDaveBio Biochemistry Tutorials: http://bit.ly/ProfDaveBiochem General Chemistry Tutorials: http://bit.ly/ProfDaveGenChem Organic Chemistry Tutorials: http://bit.ly/ProfDaveOrgChem Classical Physics Tutorials: http://bit.ly/ProfDavePhysics1 Modern Physics Tutorials: http://bit.ly/ProfDavePhysics2 Mathematics Tutorials: http://bit.ly/ProfDaveMaths American History Tutorials: http://bit.ly/ProfDaveAmericanHistory
Views: 138841 Professor Dave Explains
Gene Regulation
 
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031 - Gene Regulation Paul Andersen explains how genes are regulated in both prokaryotes and eukaryotes. He begins with a description of the lac and trp operon and how they are used by bacteria in both positive and negative response. He also explains the importance of transcription factors in eukaryotic gene expression. Do you speak another language? Help me translate my videos: http://www.bozemanscience.com/translations/ All of the images are licensed under creative commons and public domain licensing: Bioinformatik, English: Jawahar Swaminathan and MSD staff at the European Bioinformatics InstituteDeutsch: Jawahar Swaminathan und MSD Mitarbeiter am Europäischen Institut für BioinformatikPlattdüütsch: Jawahar Swaminathan un de Lüüd von MSD an dat Europääsche Institut för. English: Cartoon Representation of the Molecular Structure of Protein Registered with 2nvw Code., [object HTMLTableCellElement]. English: http://www.ebi.ac.uk/pdbe-srv/view/images/entry/2nvw600.png, displayed on http://www.ebi.ac.uk/pdbe-srv/view/entry/2nvw/summary. http://commons.wikimedia.org/wiki/File:PDB_2nvw_EBI.jpg. DNA, n.d. http://openclipart.org/detail/58543/dna-by-kumar35885. "File:E Coli at 10000x, Original.jpg." Wikipedia, the Free Encyclopedia, November 13, 2013. http://en.wikipedia.org/w/index.php?title=File:E_coli_at_10000x,_original.jpg&oldid=478393073. "File:Glass of Milk on Tablecloth.jpg." Wikipedia, the Free Encyclopedia. Accessed December 1, 2013. http://en.wikipedia.org/wiki/File:Glass_of_milk_on_tablecloth.jpg. "File:Lac operon1.png." Wikipedia, the Free Encyclopedia. Accessed December 1, 2013. http://en.wikipedia.org/wiki/File:Lac_operon1.png. "File:Protein TBP PDB 1c9b.png." Wikipedia, the Free Encyclopedia. Accessed December 1, 2013. http://en.wikipedia.org/wiki/File:Protein_TBP_PDB_1c9b.png. "File:Ribosome mRNA Translation En.svg." Wikipedia, the Free Encyclopedia. Accessed December 1, 2013. http://en.wikipedia.org/wiki/File:Ribosome_mRNA_translation_en.svg. Forluvoft. Simple Cartoon of Transcription Termination, October 9, 2007. Own work. http://commons.wikimedia.org/wiki/File:Simple_transcription_termination1.svg. Intro Music Atribution Title: I4dsong_loop_main.wav Artist: CosmicD Link to sound: http://www.freesound.org/people/CosmicD/sounds/72556/ Creative Commons Atribution License
Views: 1216417 Bozeman Science
Gene Regulation and the Order of the Operon
 
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Explore gene expression with the Amoeba Sisters, including the fascinating Lac Operon found in bacteria! Learn how genes can be turned "on" and "off" and why this is essential for cellular function. Check out our FREE video handouts on http://www.amoebasisters.com/handouts! Support us on Patreon! http://www.patreon.com/amoebasisters Our FREE resources: GIFs: http://www.amoebasisters.com/gifs.html Handouts: http://www.amoebasisters.com/handouts.html Comics: http://www.amoebasisters.com/parameciumparlorcomics Connect with us! Website: http://www.AmoebaSisters.com Twitter: http://www.twitter.com/AmoebaSisters Facebook: http://www.facebook.com/AmoebaSisters Tumblr: http://www.amoebasisters.tumblr.com Pinterest: http://www.pinterest.com/AmoebaSister­s Instagram: https://www.instagram.com/amoebasistersofficial/ Visit our Redbubble store at http://www.amoebasisters.com/store.html The Amoeba Sisters videos demystify science with humor and relevance. The videos center on Pinky's certification and experience in teaching science at the high school level. Pinky's teacher certification is in grades 4-8 science and 8-12 composite science (encompassing biology, chemistry, and physics). Amoeba Sisters videos only cover concepts that Pinky is certified to teach, and they focus on her specialty: secondary life science. For more information about The Amoeba Sisters, visit: http://www.amoebasisters.com/about-us.html We cover the basics in biology concepts at the secondary level. If you are looking to discover more about biology and go into depth beyond these basics, our recommended reference is the FREE, peer reviewed, open source OpenStax biology textbook: https://openstax.org/details/books/biology We take pride in our AWESOME community, and we welcome feedback and discussion. However, please remember that this is an education channel. See YouTube's community guidelines https://www.youtube.com/yt/policyandsafety/communityguidelines.html and YouTube's policy center https://support.google.com/youtube/topic/2676378?hl=en&ref_topic=6151248. We also reserve the right to remove comments with vulgar language. Music is this video is listed free to use/no attribution required from the YouTube audio library https://www.youtube.com/audiolibrary/music?feature=blog We have YouTube's community contributed subtitles feature on to allow translations for different languages. YouTube automatically credits the different language contributors below (unless the contributor had opted out of being credited). We are thankful for those that contribute different languages. If you have a concern about community contributed contributions, please contact us.
Views: 623468 Amoeba Sisters
Gene regulation in eukaryotes
 
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Gene regulation in eukaryotes - This lecture explains about the eukaryotic gene regulation. Regulation of gene expression entails a vast variety of mechanisms which can be utilized by cells to expand or shrink the creation of particular gene products (protein or RNA), and is informally termed gene legislation. Subtle packages of gene expression are greatly found in biology, for illustration to set off developmental pathways, reply to environmental stimuli, or adapt to new food sources. Virtually any step of gene expression can also be modulated, from transcriptional initiation, to RNA processing, and to the post-translational change of a protein. Gene regulation is main for viruses, prokaryotes and eukaryotes because it raises the flexibility and adaptability of an organism via permitting the cellphone to specific protein when needed. Although as early as 1951 Barbara McClintock confirmed interaction between two genetic loci, Activator (Ac) and Dissociator (Ds), in the color formation of maize seeds, the first discovery of a gene law approach is widely regarded to be the identification in 1961 of the lac operon, learned through Jacques Monod, in which some enzymes involved in lactose metabolism are expressed by using the genome of E. Coli handiest within the presence of lactose and absence of glucose. Furthermore, in multicellular organisms, gene regulation drives the processes of cellular differentiation and morphogenesis, main to the creation of unique cellphone forms that possess different gene expression profiles, and therefore produce one of a kind proteins/have special ultrastructures that suit them to their capabilities (although they all possess the genotype, which follows the equal genome sequence). The initiating event main to a transformation in gene expression include activation or deactivation of receptors. Additionally, there's proof that alterations in a mobile's option of catabolism results in altered gene expressions. For more information, log on to- http://www.shomusbiology.com/ Get Shomu's Biology DVD set here- http://www.shomusbiology.com/dvd-store/ Download the study materials here- http://shomusbiology.com/bio-materials.html Remember Shomu’s Biology is created to spread the knowledge of life science and biology by sharing all this free biology lectures video and animation presented by Suman Bhattacharjee in YouTube. All these tutorials are brought to you for free. Please subscribe to our channel so that we can grow together. You can check for any of the following services from Shomu’s Biology- Buy Shomu’s Biology lecture DVD set- www.shomusbiology.com/dvd-store Shomu’s Biology assignment services – www.shomusbiology.com/assignment -help Join Online coaching for CSIR NET exam – www.shomusbiology.com/net-coaching We are social. Find us on different sites here- Our Website – www.shomusbiology.com Facebook page- https://www.facebook.com/ShomusBiology/ Twitter - https://twitter.com/shomusbiology SlideShare- www.slideshare.net/shomusbiology Google plus- https://plus.google.com/113648584982732129198 LinkedIn - https://www.linkedin.com/in/suman-bhattacharjee-2a051661 Youtube- https://www.youtube.com/user/TheFunsuman Thank you for watching
Views: 163287 Shomu's Biology
Gene Regulation in Eukaryotes
 
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Donate here: http://www.aklectures.com/donate.php Website video link: http://www.aklectures.com/lecture/gene-regulation-in-eukaryotes Facebook link: https://www.facebook.com/aklectures Website link: http://www.aklectures.com
Views: 138121 AK LECTURES
Post-transcriptional Regulation of Gene Expression.mp4
 
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Video was created for a non-majors introductory biology student audience. It provides a broad overview of post-transcriptional mechanisms of gene regulation, with particular focus on alternative splicing, and protein processing/modification.
Views: 10889 sbbiovideos
Regulated Transcription
 
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NDSU Virtual Cell Animations Project animation "Regulated Transcription". For more information please see http://vcell.ndsu.edu/animations. Gene expression is controlled in many different ways. When proteins from outside a cell signal for a specific gene to be transcribed, it is known as regulated transcription. This animation illustrates how a protein like insulin can trigger a regulated transcription event, in addition to setting off the signal pathway illustrated in our Insulin Signaling video.
Views: 249957 ndsuvirtualcell
Transcription Factors - Robert Tjian (Berkeley/HHMI)
 
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https://www.ibiology.org/genetics-and-gene-regulation/transcription-factors/ Introduction to the regulatory regions and the transcription factors that bind to these regions.
Views: 4427 iBiology Techniques
Enhancers and activators for eukaryotic gene regulation
 
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Enhancers and activators for eukaryotic gene regulation
Views: 32898 HeyNow1003
How Genes are Regulated: Transcription Factors
 
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Like us on Facebook: https://www.facebook.com/pages/Stroma-Studios/290868104261105?sk=wall Each cell in our body inherits the same master copy of DNA, but different cell types use it differently. Transcription Factors help influence which genes are used in which cell. Understanding how these dynamic proteins physically interact with DNA allows us to better understand and model their binding to DNA and their regulation of gene expression. Scientific Direction by the Wasserman Lab at the University of British Columbia: http://www.cmmt.ubc.ca/research/investigators/wasserman/lab Animation and editing by Blair Lyons of Stroma Studios: http://www.stromastudios.com
Views: 320227 Blair Lyons
Transcriptional regulation : Enhancers
 
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This video describes how enhancer elements can regulate transcription from a particular promoter of a gene.
Views: 761 Arpan Parichha
Transcription Factors | A-Level Biology Tutorial | Tailored Tutors
 
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Transcription Factors explained in just a few minutes by Rich Thompson from Tailored Tutors. Watch, understand, and summarize these notes in your own revision. This video is from The Ultimate Guide To A-Level Biology - a super condensed, exam focused supplemental revision course that covers all of the new AQA, OCR, and Edexcel specification. Improve a grade in your A-Level Biology, Chemistry, or Maths course guaranteed at http://tailoredtutors.co.uk Follow us on instagram for revision tips and behind the scenes stories! instagr.am/tailoredtutors
Views: 15366 Tailored Tutors
Gene Expression
 
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A video by Genome British Columbia demonstrating gene expression www.genomicseducation.ca
Views: 507888 Genome BC
Post-transcriptional regulation | Biomolecules | MCAT | Khan Academy
 
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Created by Tracy Kim Kovach. Watch the next lesson: https://www.khanacademy.org/test-prep/mcat/biomolecules/gene-control/v/non-coding-rna-ncrna?utm_source=YT&utm_medium=Desc&utm_campaign=mcat Missed the previous lesson? https://www.khanacademy.org/test-prep/mcat/biomolecules/gene-control/v/regulation-of-transcription?utm_source=YT&utm_medium=Desc&utm_campaign=mcat MCAT on Khan Academy: Go ahead and practice some passage-based questions! About Khan Academy: Khan Academy offers practice exercises, instructional videos, and a personalized learning dashboard that empower learners to study at their own pace in and outside of the classroom. We tackle math, science, computer programming, history, art history, economics, and more. Our math missions guide learners from kindergarten to calculus using state-of-the-art, adaptive technology that identifies strengths and learning gaps. We've also partnered with institutions like NASA, The Museum of Modern Art, The California Academy of Sciences, and MIT to offer specialized content. For free. For everyone. Forever. #YouCanLearnAnything Subscribe to Khan Academy’s MCAT channel: https://www.youtube.com/channel/UCDkK5wqSuwDlJ3_nl3rgdiQ?sub_confirmation=1 Subscribe to Khan Academy: https://www.youtube.com/subscription_center?add_user=khanacademy
Views: 134281 khanacademymedicine
Operons and gene regulation in bacteria
 
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Looking at how regulatory DNA sequences can repress or promote gene transcription (particularly in bacteria operons).
Views: 170901 Khan Academy
OPERON model (regulation of gene expression)
 
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Join my best course ever https://unacademy.com/plus/course/master-biologys-most-important-topics-for-neet-aiims/08U6SJNF Watch my notes and videos https://unacademy.com/user/biologybypkagrawal-6909 https://unacademy.com/lesson/overview-in-hindi/E891HDM7 Digestion https://unacademy.com/lesson/pre-medical-exams-aiims-neet-breathing-and-exchange-of-gases-overview-in-hindi/KJXFOJ7G Breathing and exchange of gases https://unacademy.com/lesson/pre-medical-exams-aiims-neet-meaning-of-respiration-in-hindi/K12ZMK3G Meaning of respiration https://unacademy.com/lesson/body-fluids-and-circulation-2-blood-vessels-in-hindi/YD3DIWR3 Circulation https://unacademy.com/lesson/lesson-1-nucleotides-and-their-structure-in-hindi/U1CE5WFA Nucleic acid https://unacademy.com/lesson/course-overview-in-hindi/C2ZTSPZQ Muscles
Views: 70555 BIOLOGY BY P K AGRAWAL
Gene regulation in prokaryotes
 
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This lecture explains about the Gene regulation in prokaryotes. Regulation of gene expression entails a broad range of mechanisms that are used by cells to develop or diminish the production of specific gene products (protein or RNA), and is informally termed gene legislation. Subtle applications of gene expression are greatly located in biology, for example to trigger developmental pathways, respond to environmental stimuli, or adapt to new food sources. Practically any step of gene expression may also be modulated, from transcriptional initiation, to RNA processing, and to the put up-translational amendment of a protein. Gene law is main for viruses, prokaryotes and eukaryotes as it raises the flexibility and suppleness of an organism via allowing the mobile to express protein when wanted. Despite the fact that as early as 1951 Barbara McClintock confirmed interplay between two genetic loci, Activator (Ac) and Dissociator (Ds), within the color formation of maize seeds, the primary discovery of a gene legislation procedure is largely regarded to be the identification in 1961 of the lac operon, learned by means of Jacques Monod, where some enzymes concerned in lactose metabolism are expressed with the aid of the genome of E. Coli most effective in the presence of lactose and absence of glucose. Furthermore, in multicellular organisms, gene legislation drives the approaches of mobile differentiation and morphogenesis, leading to the creation of specific mobilephone types that possess distinct gene expression profiles, and as a consequence produce distinctive proteins/have different ultrastructures that swimsuit them to their features (though all of them possess the genotype, which follows the equal genome sequence). The initiating event leading to a change in gene expression comprise activation or deactivation of receptors. Also, there may be evidence that alterations in a cell's choice of catabolism results in altered gene expressions. For more information, log on to- http://www.shomusbiology.com/ Get Shomu's Biology DVD set here- http://www.shomusbiology.com/dvd-store/ Download the study materials here- http://shomusbiology.com/bio-materials.html Remember Shomu’s Biology is created to spread the knowledge of life science and biology by sharing all this free biology lectures video and animation presented by Suman Bhattacharjee in YouTube. All these tutorials are brought to you for free. Please subscribe to our channel so that we can grow together. You can check for any of the following services from Shomu’s Biology- Buy Shomu’s Biology lecture DVD set- www.shomusbiology.com/dvd-store Shomu’s Biology assignment services – www.shomusbiology.com/assignment -help Join Online coaching for CSIR NET exam – www.shomusbiology.com/net-coaching We are social. Find us on different sites here- Our Website – www.shomusbiology.com Facebook page- https://www.facebook.com/ShomusBiology/ Twitter - https://twitter.com/shomusbiology SlideShare- www.slideshare.net/shomusbiology Google plus- https://plus.google.com/113648584982732129198 LinkedIn - https://www.linkedin.com/in/suman-bhattacharjee-2a051661 Youtube- https://www.youtube.com/user/TheFunsuman Thank you for watching
Views: 99030 Shomu's Biology
DNA and chromatin regulation | Biomolecules | MCAT | Khan Academy
 
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Created by Tracy Kim Kovach. Watch the next lesson: https://www.khanacademy.org/test-prep/mcat/biomolecules/gene-control/v/regulation-of-transcription?utm_source=YT&utm_medium=Desc&utm_campaign=mcat Missed the previous lesson? https://www.khanacademy.org/test-prep/mcat/biomolecules/gene-control/v/jacob-monod-the-lac-operon?utm_source=YT&utm_medium=Desc&utm_campaign=mcat MCAT on Khan Academy: Go ahead and practice some passage-based questions! About Khan Academy: Khan Academy offers practice exercises, instructional videos, and a personalized learning dashboard that empower learners to study at their own pace in and outside of the classroom. We tackle math, science, computer programming, history, art history, economics, and more. Our math missions guide learners from kindergarten to calculus using state-of-the-art, adaptive technology that identifies strengths and learning gaps. We've also partnered with institutions like NASA, The Museum of Modern Art, The California Academy of Sciences, and MIT to offer specialized content. For free. For everyone. Forever. #YouCanLearnAnything Subscribe to Khan Academy’s MCAT channel: https://www.youtube.com/channel/UCDkK5wqSuwDlJ3_nl3rgdiQ?sub_confirmation=1 Subscribe to Khan Academy: https://www.youtube.com/subscription_center?add_user=khanacademy
Views: 122347 khanacademymedicine
Gene Regulation and the Lac Operon
 
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Donate here: http://www.aklectures.com/donate.php Website video link: http://www.aklectures.com/lecture/gene-regulation-and-the-lac-operon Facebook link: https://www.facebook.com/aklectures Website link: http://www.aklectures.com
Views: 95373 AK LECTURES
Post Transcriptional control of gene expression
 
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This video is about Post-transcriptional control of gene expression. Cells with a nucleus contain DNA with genetic information. This information is past on to mRNA by transcription. RNA processing The DNA strand is made up of exons and introns. Exon codes for an amino acid but introns do not. During transcription both exons and introns are transcribed to mRNA. This RNA is called pre-mRNA because of the exons and introns present in its strand. During the process of splicing the introns are removed by specific enzymes . As a result only exons remain in the mature mRNA. Research resources: OCR A A-Level Biology cgpbooks(2015) A Level Biology for OCR. Oxford University Press (2015)
Views: 209 Brian Caesar
04 The Transcriptional Regulation of Gene Expression in Eukaryotes
 
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Video Index. Basic Mechanisms of Eukaryotic Transcriptional Activation 4m12s Positive Regulation of Eukaryotic Promoters 23m43s Combinatorial Control of Gene Expression (galactose genes) 47m48s Combinatorial Control of Gene Expression (Yeast MAT locus) 58m13s Combinatorial Mixtures of Heterodimers Regulate Transcription 1h9m29s Differentiation Requires Extensive Use of Combinatorial Control 1h15m25s Insulators and gene silencing 1h34m37s Steroid Hormone receptors are transcription activators (recap) 1h40m50s
Views: 19663 Mark Temple
A2 Biology - Post-transcriptional control of gene expression (OCR A Chapter 19.2)
 
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The second level of gene expression regulation is after transcription, where the pre-mRNA is edited for translation. There are a few steps that can be done: RNA splicing to remove introns (saving time and resources), adding a cap and poly-adenine tail (to stablise RNA) and RNA editing (to produce proteins of different structures and functions). Here we'll have a look at these processes. Please subscribe for more content and comment below to let me know what you think! :) Facebook: BioRach - A-level Biology Online https://www.facebook.com/biorachproject/ Twitter: @BioRachProject https://twitter.com/BioRachProject?lang=zh-tw Background music: Enchanted Journey by Kevin MacLeod is licensed under a Creative Commons Attribution licence (https://creativecommons.org/licenses/by/4.0/) Source: http://incompetech.com/music/royalty-free/index.html?isrc=USUAN1100799 Artist: http://incompetech.com/
Views: 1020 BioRach
GENETICS 3: GENE REGULATION: POST-TRANSCRIPTIONAL REGULATION
 
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GENE REGULATION: POST-TRANSCRIPTIONAL REGULATION
Views: 4564 Walter Jahn
Eukaryotic regulation of gene expression
 
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Discussing additional mechanisms that eukaryotes have to control how often genes are expressed, and how often mRNAs are translated. This includes discussing additional DNA regulatory regions (enhancers, silencers), histone packing / unpacking, and RNA interference
Views: 110484 BleierBiology
Transcriptional Regulation in Eukaryotes
 
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Animation describing 5 processes involved in transcription regulation: - Transcription initiation - Chromatin Re-modelling - Genomic Imprinting - RNA interference using microRNA's - Regulation of Transcription by Steroid Hormones
Views: 2694 Joseph Cavell
Control of Gene Expression
 
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Examines transcriptional, post transcriptional, translational, and post translational control over protein synthesis.
Views: 16529 knowwhatuknow41
Gene Expression: Transcription & Translation
 
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By McGraw Hill Publication's
Views: 16110 BIOISHK
Eukaryotic Regulation of Gene Expression
 
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Moof's Medical Biochemistry Video Course: http://moof-university.thinkific.com/courses/medical-biochemistry-for-usmle-step-1-exam
Views: 33623 Moof University
Robert Tjian (Berkeley/HHMI) Part 2: Gene regulation: Why so complex?
 
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https://www.ibiology.org/genetics-and-gene-regulation/transcription-factors/#part-2 Transcription, the conversion of DNA to RNA, is one of the most fundamental processes in cell biology. However, only about 3% of our total DNA encodes genes to be transcribed. RNA polymerase II, the enzyme that transcribes DNA to RNA, relies on a large set of proteins known as transcription factors to recognize the coding sequences and to transcribe the correct genes, in the correct cell type, at the correct time. In Part 1 of his lecture, Tjian gives an overview of the complex and critical role that transcription factors play in regulating gene expression. How do different cells from the same organism, such as muscle cells, neurons and red blood cells, all of which have identical DNA, have such different phenotypes? Tjian addresses this question in his second lecture, where he expands on the mechanisms of gene regulation.
Views: 27941 iBiology
Transcription regulation
 
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In this animation, we explore the ways in which the expression of genes can be regulated. http://ukcatalogue.oup.com/product/9780199658572.do
Prokaryotic Transcription (Part 1 of 5) - Transcriptional Regulation
 
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Moof's Medical Biochemistry Video Course: http://moof-university.thinkific.com/courses/medical-biochemistry-for-usmle-step-1-exam
Views: 24088 Moof University
Transcription Regulation via Histone Modifications
 
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Welcome! Through this video I hope to explain some mystifying concepts about nucleosomes, and how these eight-part microscopic proteins help control the wide variety of life we see today through regulation of transcription.
Views: 3133 Sarah Montalbano
Lac Operon - gene regulation in prokaryotes
 
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This lecture explains the lac operon and the regulation of gene expression in prokaryotes by lac operon. The lac operon consists of three structural genes, and a promoter, a terminator, regulator, and an operator. The three structural genes are: lacZ, lacY, and lacA. lacZ encodes β-galactosidase (LacZ), an intracellular enzyme that cleaves the disaccharide lactose into glucose and galactose. This video lecture will teach you the mechanism of lac operon. It will also explain the positive and negative regulation of Lac operon and how it is controlled in response to the presence of Glucose. This video will also help you to realize the difference between a catabolic and an anabolic operon. For more information, log on to- http://www.shomusbiology.com/ Get Shomu's Biology DVD set here- http://www.shomusbiology.com/dvd-store/ Download the study materials here- http://shomusbiology.com/bio-materials.html Remember Shomu’s Biology is created to spread the knowledge of life science and biology by sharing all this free biology lectures video and animation presented by Suman Bhattacharjee in YouTube. All these tutorials are brought to you for free. Please subscribe to our channel so that we can grow together. You can check for any of the following services from Shomu’s Biology- Buy Shomu’s Biology lecture DVD set- www.shomusbiology.com/dvd-store Shomu’s Biology assignment services – www.shomusbiology.com/assignment -help Join Online coaching for CSIR NET exam – www.shomusbiology.com/net-coaching We are social. Find us on different sites here- Our Website – www.shomusbiology.com Facebook page- https://www.facebook.com/ShomusBiology/ Twitter - https://twitter.com/shomusbiology SlideShare- www.slideshare.net/shomusbiology Google plus- https://plus.google.com/113648584982732129198 Thank you for watching the video lecture on Lac operon and regulation of lac operon.
Views: 307306 Shomu's Biology
Control of Gene Expressions in Bacteria
 
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Topic: Control of gene expression in bacteria: positive vs negative control and inducible vs repressible Group: Isabela Alesna, Bo-Sung Kim, Midori Yoshino We’ll be covering the “Control of gene expression in bacteria”: This happens through transcriptional control and operon control . Before we jump into the process, let’s define things first. In the control of gene expression, there are a few key players: the operon, promoter, operator, structural genes, regulatory gene, and regulatory protein. An operon is a group of bacterial structural genes and sequences that control transcription of those genes into a single mRNA. Within the operon is then a promoter, a sequence that RNA polymerase can recognize and bind to. An operator, which is the place where a regulatory protein can bind to turn the operon on or off. And structural genes, the sequences that encode for protein. A regulatory gene, located outside of the operon, is a sequence that makes the regulatory protein which as we said before binds to the operator This will all make more sense in a bit! So back to talking about the actual gene expression! There are 2 types of transcriptional control. Negative control and Positive control. In both cases the regulatory protein acts like an on/off switch. Negative control is when the regulatory protein is a repressor. It binds to the operon and inhibits transcription. Like a switch, the regulatory protein turns gene expression off. And Positive control is when the regulatory protein is an activator. It binds to the operon and and stimulates transcription. Like a switch, the regulatory protein turns gene expression on. Now there are 2 types of operon control. Inducible operon and Repressible operon. First, there is the inducible operon. Here, gene expression is usually turned off either by an active repressor or an inactive activator. It can be induced, aka turned on. Then there is the repressible operon. Here, gene expression is usually turned on either by an inactive repressor or an active activator. It can be repressed, aka turned off. Let’s put it all together! In summary, there is Negative Inducible, Positive Inducible, Negative Repressible, and Positive Repressible. Negative Inducible is when the regulatory protein is an active repressor is bound to the operon, and transcription is off. Positive Inducible is when the regulatory protein is an inactive activator and is not bound to the operon, and transcription is off. In both of these cases, they can be INDUCED (or encouraged) to be turned on. Negative Repressible is when the regulatory protein is an inactive repressor, does not bind to the operon, and transcription is on. Positive Repressible is when the regulatory protein is an active activator, binds to the operon, and transcription is on. In both of these cases, they can be REPRESSED (or restrained) to be turned off. Let’s look at a specific example of negative inducible. The most popular negative inducible system is the lac operon. The lac operon is responsible for making enzymes that break down lactose. When there isn’t any lactose around, the lac operon is turned off--there’s no need to make that protein if it won’t be doing anything. Therefore the repressor is bound to the operator, inhibiting transcription of the gene. BUT. when a lactose (allolactose) is present, it binds to the repressor. The repressor protein changes its shape and becomes inactive, meaning it cannot bind to the operator. Therefore, the gene is turned on and makes a series of enzymes which can then break down the lactose. Let’s look at an example for negative repressible, dealing with Tryptophan. The trp operon is responsible for controlling biosynthesis of the amino acid tryptophan, in E. coli. When tryptophan level is low, the repressor is inactive and cannot bind to the operator. So the gene expression is turned on. Transcription takes place and more tryptophan is synthesized. When tryptophan level is high, tryptophan binds to the inactive repressor, making it active. The repressor then binds to the operator and turn off the gene expression. Hope you liked our video on the Control of gene expression in bacteria!
Views: 34830 Bo-Sung Kim
miRNA biogenesis - brief introduction into post-transcriptional regulation of gene expression
 
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Speaker: Lukasz Sobkowiak, PhD, Poland miRNA biogenesis - brief introduction into post-transcriptional regulation of gene expression. BIBLIOGRAPHY: [1] Cell 173 2018 doi.org/10.1016/j.cell.2018.03.006 [2] Cell 2016 doi.org/10.1016/j.cell.2015.12.019 [3] Cell 2017 doi.org/10.1016/j.cell.2017.02.015 [4] Cell 2013, doi: 10.1016/j.cell.2013.11.027 [5] RNA 2011 doi: 10.1261/rna.2732611 [6] Science 2009 doi: 10.1126/science.1178705 [7] Molecular Cell 2011 doi: 10.1016/j.molcel.2011.09.012. [8] Nature Struct & Mol Biol 2014 doi: 10.1038/nsmb.2862. [9] PNAS 2008 doi: 10.1073/pnas.0711506105 [10] Nature 2011 doi: 10.1038/nature10198 [11] Current Biology 2011 doi: 10.1016/j.cub.2011.09.034 [12] Curr Biol. 2011 doi: 10.1016/j.cub.2011.10.006 [13] Cell Report 2013 doi.org/10.1016/j.celrep.2013.05.033 [14] NAR 2017, doi: 10.1093/nar/gkx916 [15] Science 2012 doi: 10.1126/science.1221551 [16] https://www.youtube.com/watch?v=9v-13EZWVk8 [17] Movie: http://www.katharinapetsche.com/ Molecular animations: PyMOL Molecular Graphics System version 1.7.2.1 (Schrodinger) on Linux Ubuntu version 16.04 LTS.
Views: 301 Sobkoluk 84
Prokaryotic regulation of gene expression
 
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How prokaryotes regulate how actively their genes are expressed (on or off, up or down). I discuss both negative gene regulation (involving repressors) and positive gene regulation (involving activators), discussing the classic trp and lac operon systems where this was first studied.
Views: 43311 BleierBiology
Post-Transcriptional Modification (2016) IB Biology
 
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7.1 DNA structure and replication: Post-Transcriptional Modification Understanding that: -Eukaryotic cells modify mRNA after transcription -The regions of DNA that do not code for proteins should be limited to regulators of gene expression, introns, telomeres and genes for tRNAs -Splicing of mRNA increases the number of different proteins an organism can produce
Views: 21863 Alex Lee
Robert Tjian (Berkeley/HHMI) Part 1: Gene regulation: An introduction
 
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https://www.ibiology.org/genetics-and-gene-regulation/transcription-factors/ Transcription, the conversion of DNA to RNA, is one of the most fundamental processes in cell biology. However, only about 3% of our total DNA encodes genes to be transcribed. RNA polymerase II, the enzyme that transcribes DNA to RNA, relies on a large set of proteins known as transcription factors to recognize the coding sequences and to transcribe the correct genes, in the correct cell type, at the correct time. In Part 1 of his lecture, Tjian gives an overview of the complex and critical role that transcription factors play in regulating gene expression. How do different cells from the same organism, such as muscle cells, neurons and red blood cells, all of which have identical DNA, have such different phenotypes? Tjian addresses this question in his second lecture, where he expands on the mechanisms of gene regulation.
Views: 57458 iBiology
Biol 360 Tutorial General Positive Negative gene regulation
 
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Made with Explain Everything
Views: 3900 Cindy Malone